Individuals without diabetes can consume Glucerna products. Abbott Nutrition has many other options, such as Ensure, ZonePerfect, or EAS, for people without diabetes to integrate into their meal plans. However, Glucerna shakes and bars are specially designed for people with diabetes. Glucerna products are intended to be used under medical supervision to support the dietary management of diabetes.

The Glucerna portfolio contains blends of carbohydrates which include modified maltodextrin (a portion of the maltodextrin has been modified so the body is not able to digest it), fructose, maltitol, soy fiber and fructooligosaccaharides. This helps minimize the peak in blood glucose. This carbohydrate that is not digested may be fermented in the large intestine. These ingredients, in combination with the other carbohydrates listed above, produces a lower blood glucose response compared to a higher glycemic carbohydrate. Refer to individual product labeling for specific ingredient information. Ingredients will vary per product and flavor.